West Nile virus – how dangerous is this disease?

The West Nile virus is transmitted by mosquitoes between birds, but also to humans, horses, and other mammals. For a long time, it only occurred on the African continent. However, since 1999, the West Nile virus has also spread to the US. In 2018, it was detected for the first time in birds and two horses in Germany (Saxony and Saxony-Anhalt). Since then, infections have occurred in the summer and fall months. Berlin, Brandenburg, Saxony-Anhalt, and Saxony are particularly affected. However, more and more cases are now also occurring in Thuringia, Mecklenburg-Western Pomerania, Hamburg, Schleswig-Holstein, Lower Saxony, Rhineland-Palatinate, and Bavaria. West Nile infection is a notifiable animal disease.

INHALT
Cause, transmission, and development Symptoms Diagnosis Treatment Prophylaxis
Cause, transmission, and development

The West Nile virus multiplies in birds. It spreads through blood-sucking mosquitoes, mainly among wild birds. However, infected mosquitoes also transmit the virus to humans, horses, and other mammals. These, however, offer poor conditions for the virus to multiply. They are referred to as dead-end hosts. The virus is not transmitted further from these hosts. Due to the seasonal increase in insect activity, infections usually occur in summer and fall. They are particularly common in years with hot, humid summers.

Schematic representation of West Nile virus transmission
1 Host (bird) | 2 Vector (mosquito) | 3 False hosts (e.g., humans, horses)
Symptoms

In most cases, the infection does not cause any visible symptoms in horses. However, in eight to ten percent of cases, fever and severe neurological symptoms occur. These include, among other things:

  • Hyperactivity
  • Muscle tremors
  • Ataxia (=disturbed gait, see corresponding article) to the point of recumbency
  • Swallowing disorders
  • Head tilt
  • Increased sensitivity to light

One quarter to half of neurologically affected animals die. In rare cases, horses develop a general illness with fever but no neurological symptoms.

Diagnosis

Since West Nile virus infections are largely asymptomatic, they usually go undetected. If neurological symptoms occur, your vet will perform a general and neurological examination of your horse. The vet will take blood samples to detect the virus or antibodies against the virus. These samples will be sent to official laboratories for testing. Diseases with similar symptoms, such as Borna, tumors, or liver disease, will be ruled out through further tests.

Treatment

West Nile disease is a notifiable animal disease. Therefore, the official veterinarian must be notified as soon as the disease is suspected. There is no medication against the West Nile virus itself. Your veterinarian will treat infected horses with anti-inflammatory drugs and other measures to alleviate the symptoms. It is important to keep the horse in a quiet environment in the stable.

Prophylaxis

The most effective protection is vaccination. It does not prevent infection, but it reduces the duration and severity of the disease. The Standing Committee on Vaccination in Veterinary Medicine (StiKo Vet) recommends vaccinating all horses kept in or transported to areas already affected by West Nile virus or in the immediate vicinity. On January 6, 2025, Stiko Vet updated its guidelines for vaccinating horses based on the current outbreak situation. The vaccination recommendation was extended to the entire North German lowlands. In the medium term, the goal is to vaccinate all horses in Germany, as the West Nile virus continues to spread. Therefore, please check the Friedrich-Löffler-Institut (=FLI) website regularly for the latest information on the spread of the virus and the StIKo Vet website for the latest vaccination recommendations.

As the virus is not transmitted from horse to horse, it is not necessary to vaccinate the entire herd. After the initial immunization, individual animals are very well protected. Vaccination takes place in the spring before the start of the mosquito season. Depending on the vaccine, horses can be vaccinated from the age of five or six months. Two vaccinations are required for basic immunization, with an interval of three to six weeks between vaccinations. Depending on the vaccine, protection begins two to three weeks after the second vaccination or four weeks after the first vaccination. The West Nile vaccination must be refreshed annually before the start of the mosquito season.

Your vet can send you a vaccination schedule via petsXL. You will then automatically receive notifications when it is time to make another appointment.

You can also protect your horse from mosquitoes with fly sheets and insect repellents (see related article). Do not put horses in high-risk areas on pastures near water, as insects breed particularly well there. Remove any standing water in the stable area.