Botulism – not an infection, but poisoning

Botulism refers to illnesses caused by metabolic products of bacteria of the genus Clostridium botulinum. Strictly speaking, it is not an infection but rather a form of poisoning, as it is not the bacteria that enter the body but their toxins, which are among the most poisonous biological substances known to man. Many of us are familiar with this toxin only as "Botox" used in cosmetic surgery, where it is administered in very low doses to smooth wrinkles.

INHALT
Causes Origin Symptoms Diagnosis Treatment Forecast Prophylaxis
Causes

The pathogen is the bacterium Clostridium botulinum, which is widespread in the environment and also occurs in the intestinal flora of healthy animals and humans. The main source of transmission for cattle and horses, but also for dogs and cats, is feed contaminated by animal carcasses (e.g., birds, deer) or water from which the animals drink or with which they come into contact. The pathogen can multiply particularly well in protein-rich food and in the absence of air, such as in canned food or packaged sausage products. This explains the name, as "botulus" is Latin for sausage.

Origin

The toxin is produced by Clostridia outside the organism and ingested by animals through food. Since it is not an infectious disease, it is not transmitted from animal to animal. The toxin enters the bloodstream via the gastrointestinal tract, where it spreads throughout the body. The toxin mainly attacks the nerve cells, damaging them to such an extent that signal transmission between the nerves and muscles is disrupted.

Symptoms

The first symptoms of the disease appear a few hours to days after ingestion of the toxin. The main symptoms are paralysis of the muscles, which usually begins in the rear half of the body. As the disease progresses, movement and coordination disorders, excessive salivation, and problems with eating develop. Characteristically, there is no fever and the animals remain fully conscious, as the poison does not cross the blood-brain barrier.

The severity of the symptoms depends on the amount of poison ingested. If you suspect that your dog has ingested contaminated water or is already showing signs of paralysis, take the animal to a veterinarian as soon as possible. The sooner the disease is recognized and treated, the better the chances of recovery. If immediate action is not taken, the worst-case scenario is paralysis of the respiratory muscles, leading to an agonizing death by suffocation.

Diagnosis

If botulism is suspected, it is extremely important to provide your veterinarian with a detailed preliminary report. In particular, information about the possible consumption of canned food, sausage products, animal carcasses, or drinking from contaminated water can give the veterinarian clues about the possible cause of the illness.

Based on their examination, the characteristic symptoms observed, and your preliminary report, your veterinarian will be able to make an initial clinical diagnosis. To confirm the diagnosis, the toxin must be detected in body fluids or organ samples, which, however, can only be done by specialized laboratories due to the testing method. Due to the widespread nature of the pathogen, bacterial detection is not considered reliable.

Treatment

There is no specific treatment for botulism. The aim of treatment must always be to remove as much of the toxin as possible from the digestive tract. This is achieved by administering laxatives and enemas. Antidotes can be administered to inactivate the toxin circulating freely in the blood. The sooner treatment begins, the better the chances of recovery, as the toxin that has already bound to nerve cells cannot be inactivated. If the symptoms of paralysis are already advanced, only symptomatic treatment is possible. Circulation and breathing must be stabilized and any fluid deficiency must be corrected.

Forecast

The prognosis depends greatly on the amount of poison ingested and when treatment begins. With early intervention and a small amount of poison, the chances of a complete recovery are relatively good, although it can take months for the symptoms of paralysis to disappear. If treatment is not started until the poisoning is at an advanced stage, there is usually little hope for the patient, as the poison has already affected the respiratory and heart muscles, leading to death.

Prophylaxis

To prevent botulism, hygienic feeding is paramount. For cattle and horses, it is important to ensure that feed storage areas, stables, pastures, and drinking troughs are kept free of animal carcasses at all times and that mice and rats are controlled properly.

The best measure to protect your dog from botulism poisoning from the environment is training. If your dog has learned not to drink from puddles or standing water and not to eat anything lying around outside, you have already significantly reduced the risk of poison ingestion.

Since many dogs and cats are now fed raw meat, it is particularly important to handle the meat correctly when thawing it. Vacuum-packed, frozen meat should be thawed slowly in the refrigerator and not at room temperature or even in warm water, where bacteria can multiply rapidly and toxins can form.